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《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:

2021年01期

页码:

37-41

栏目:

基础研究

出版日期:

2021-01-20

文章信息/Info

Title:

Effect of estrogen on vascular calcification in ovariectomized rats

作者:

吴新华; 刘权仪; 刘宏; 陈章荣; 杨伟; 赵秋燕; 李文彬

671000 大理大学第一附属医院心血管内科(吴新华,刘宏,陈章荣,赵秋燕); 516000 惠州第三人民医院心血管内科(刘权仪); 453000 新乡医学院第三附属医院心血管内科(杨伟); 671000 中国人民解放军云南大理军分区干休所(李文彬)

Author(s):

WU Xinhua¹;  Liu Quanyi²;  LIU Hong¹;  CHEN Zhangrong¹;  YANG Wei³;  ZHAO Qiuyan¹;  LI Wenbin⁴.

1.Department of Cardiology, First Affiliated Hospital of Dali University, Dali 671000; 2.Department of Cardiology, Huizhou Third People’s Hospital, Huizhou 516000; 3.Department of Cardiology, Third Affiliated Hospital of Xinxiang Medical College, Xinxiang

关键词:

雌激素;  血管钙化;  Runt相关转录因子2

Keywords:

Estrogen;  Vascular calcification;  Runt-related transcription factor 2

分类号:

-

DOI:

10.3969/j.issn.1673-6583.2021.01.010

文献标识码:

-

摘要:

目的:探讨雌激素对去卵巢大鼠血管钙化的影响。方法:将40只雌性SD大鼠随机分为5组,每组8只。空白对照组正常喂养。去卵巢钙化组、β₂雌二醇(E₂)溶媒对照组和E₂干预组均切除双侧卵巢,假手术钙化组切除卵巢周围等体积的脂肪组织,术后给予维生素D₃ 30万U·kg^-1·d^-1注射3 d建立血管钙化模型。E₂溶媒对照组和E₂干预组分别给予

Abstract:

Objective:To investigate the effect of estrogen on vascular calcification in rats.Methods:Fourty female SD rats were randomly divided into 5 groups with 8 rats in each group. The blank control group was given normal feeding. Except of the mice in the sham

参考文献/References

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备注/Memo

备注/Memo:

基金项目:国家自然科学基金(81560073)
通信作者:刘宏,E-mail: daliliuhong@163.com

常用功能

更新日期/Last Update: 2021-01-20