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《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:

2021年05期

页码:

306-311

栏目:

临床研究

出版日期:

2021-10-01

文章信息/Info

Title:

Value of non-invasive pressure-strain loop for assessing right heart function and prognosis in patients with pulmonary arterial hypertension

作者:

王俭;杨梦慧;孙灵跃;乔志卿;沈学东;沈节艳

200127 上海交通大学医学院附属仁济医院心内科

Author(s):

WANG Jian;  YANG Menghui;  SUN Lingyue;  QIAO Zhiqing;  SHEN Xuedong;  SHEN Jieyan

Department of Cardiology, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China

关键词:

肺动脉高压;  无创性压力-应变环;  心肌做功;  右心功能;  预后

Keywords:

Pulmonary arterial hypertension;  Non-invasive pressure-strain loop;  Myocardial work;  Right heart function;  Prognosis.

分类号:

-

DOI:

10.3969/j.issn.1673-6583.2021.05.013

文献标识码:

-

摘要:

目的:探究无创性压力-应变环(PSL)技术用于评估肺动脉高压(PAH)患者右心功能和预后的价值。方法:2018年1月至2020年6月连续纳入52例PAH患者,完成常规经胸心脏彩超检查,使用PSL获得右心心肌做功参数,包括右室整体做功效率(RVGWE)、右室整体做功指数(RVGWI)、右室整体有用功(RVGCW)和右室整体无用功(RVGWW)。分析心肌做功参数与临床心功能评估参数的相关性。所有患者随访至2021年1月。分析心肌做功参数评估患者预后的价值。结果:相关性分析显示,心肌做功参数与临床心功能评估参数具有良好相关性(P<0.05)。所有患者随访395.0(266.5,415.8)d,COX多因素回归模型显示,RVGWE是患者临床预后的独立保护因素(HR=0.887,95%CI 0.794～0.992,P=0.035)。ROC曲线分析显示,RVGWE对于患者预后的预测价值最高(AUC=0.872, P<0.001),RVGWW次之(AUC=0.840, P<0.001)。生存分析显示,RVGWE≤81.5%或RVGWW≥177.0 mmHg%者(log-rank P<0.001)更易发生临床恶性事件。结论:PSL可以很好地评估PAH患者右心功能,心肌做功参数RVGWE和RVGWW是预测患者临床结局的有效指标。

Abstract:

Objective:To investigate the value of non-invasive pressure-strain loop(PSL)technique for assessing right heart function and prognosis in patients with pulmonary arterial hypertension(PAH).Methods:Fifty-two patients with PAH were enrolled consecutively fr

参考文献/References

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备注/Memo

备注/Memo:

基金项目:国家自然科学基金面上项目(81970047); 国家自然科学基金青年项目(81800048); 上海交通大学医学院附属仁济医院临床科研创新培育基金(PYII20-13)
通信作者:沈节艳,E-mail:shenjieyan@renji.com

常用功能

更新日期/Last Update: 2021-10-01