[1]付祥雯,孙慧.钠-葡萄糖共转运蛋白2抑制剂在射血分数
保留的心力衰竭治疗中的应用[J].国际心血管病杂志,2024,03:156-159.
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钠-葡萄糖共转运蛋白2抑制剂在射血分数
保留的心力衰竭治疗中的应用(PDF)
《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]
- 期数:
- 2024年03期
- 页码:
- 156-159
- 栏目:
- 综述
- 出版日期:
- 2024-05-20
文章信息/Info
- Title:
- -
- Author(s):
- -
- 关键词:
- 射血分数保留的心力衰竭; 钠- 葡萄糖共转运蛋白2 抑制剂; 病理生理机制
- Keywords:
- -
- 分类号:
- -
- DOI:
- 10.3969/j.issn.1673-6583.2024.03.008
- 文献标识码:
- -
- 摘要:
- 射血分数保留的心力衰竭（HFpEF）是因左室舒张期充盈受损和心肌顺应性降 低而引起的心力衰竭。HFpEF 的治疗主要以缓解症状为主，钠- 葡萄糖共转运蛋白2 抑制剂 （SGLT2i）可通过提高肥胖与运动耐受力、改善心肌细胞纤维化与能量代谢、拮抗心房颤动、 抑制交感系统及巨噬细胞活化等途径，治疗HFpEF 并改善其预后。该文介绍HFpEF 的病理 生理机制及SGLT2i 在HFpEF 治疗中的进展。
- Abstract:
- -
参考文献/References
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备注/Memo
- 备注/Memo:
-
基金项目：山东省医药卫生科技发展计划项目（202003011255）
通信作者：孙慧，E-mail: Sasa303@163.com
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