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[1]朵杰,白洁,韩琼.微小RNA-17-5p通过靶向调控TP53INP1的表达对 急性心肌梗死后心室重构的影响[J].国际心血管病杂志,2022,02:112-116.
　DUO Jie,BAI Jie,HAN Qiong..The effect of miR-17-5p on ventricular remodeling after acute myocardial infarction by targeting the expression of TP53INP1[J].International Journal of Cardiovascular Disease,2022,02:112-116.
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微小RNA-17-5p通过靶向调控TP53INP1的表达对 急性心肌梗死后心室重构的影响(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2022年02期
页码:
112-116
栏目:
综述
出版日期:
2022-06-01

文章信息/Info

Title:
The effect of miR-17-5p on ventricular remodeling after acute myocardial infarction by targeting the expression of TP53INP1
作者:
朵杰; 白洁; 韩琼
目的：探讨微小RNA（miRNA）miR-17-5p 通过靶向调控肿瘤蛋白53 诱导性 核蛋白1（TP53INP1）的表达对急性心肌梗死（AMI）后心室重构的影响。方法：选取成年 miR-17-5p-/-、miR-17-5p＋/＋和正常型SPF 级昆明种小鼠各20 只，采用随机数字表法分为假 手术组、AMI 组、miR-17-5p-/- 假手术组、miR-17-5p-/-AMI 组，miR-17-5p＋/＋假手术组和 miR-17-5p＋/＋AMI 组，每组10 只，雌雄各半。构建小鼠AMI 模型，采用超
Author(s):
DUO Jie;  BAI Jie;  HAN Qiong.
Department of Hypertension, Qinghai Cardiovascular and Cerebrovascular Disease Hospital, Xining 810000, China
关键词:
-
Keywords:
MiR-17-5p;  Tumor protein 53-inducible nuclear protein 1;  Acute myocardial infarction;  Ventricular remodeling
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2022.02.015
文献标识码:
-
摘要:
微小RNA-17-5p ；肿瘤蛋白53 诱导性核蛋白1 ；急性心肌梗死；心室重构
Abstract:
Objective: To investigate the effect of miR-17-5p on ventricular remodeling after acute myocardial infarction (AMI) by targeting the expression level of tumor protein 53-inducible nuclear protein 1 (TP53INP1). Methods: Twenty adult Kunming SPF mice with m

参考文献/References

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备注/Memo

备注/Memo:
作者单位：810000 西宁, 青海省心脑血管病专科医院高血压科
通信作者：朵杰, E-mail:commendf@sina.com
更新日期/Last Update: 2022-06-01