|本期目录/Table of Contents|

[1]吴佳伟,范怡伦,丁丹,等.睾丸特异性Y编码蛋白5在心肌缺血损伤中的作用[J].国际心血管病杂志,2021,04:236-240.
　WU Jiawei,FAN Yilun,DING Dan,et al.The role of TSPYL5 in myocardial ischemia injury[J].International Journal of Cardiovascular Disease,2021,04:236-240.
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睾丸特异性Y编码蛋白5在心肌缺血损伤中的作用(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2021年04期
页码:
236-240
栏目:
基础研究
出版日期:
2021-08-15

文章信息/Info

Title:
The role of TSPYL5 in myocardial ischemia injury
作者:
吴佳伟; 范怡伦; 丁丹; 薛松; 黄日太
200120 上海交通大学医学院附属仁济医院心血管外科
Author(s):
WU Jiawei;  FAN Yilun;  DING Dan;  XUE Song;  HUANG Ritai
Department of Cardiovascular Surgery,Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200120, China
关键词:
心肌缺血;  睾丸特异性Y编码蛋白5;  缺氧;  p53
Keywords:
Myocardial ischemia;  Testis-specific Y-encoded-like protein 5;  Hypoxia;  p53
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2021.04.012
文献标识码:
-
摘要:
目的:探讨睾丸特异性Y编码蛋白5(TSPYL5)在心肌缺血损伤中的作用及机制。方法:在体内实验中,构建心肌缺血小鼠模型,采用实时荧光定量聚合酶链反应(qRT-PCR)、Western blot和免疫组织化学染色等方法检测正常对照组和心肌缺血组小鼠心肌组织中TSPYL5的表达情况。在体外实验中,将HL-1细胞分成4组:空白对照组、TSPYL5过表达组、化学缺氧组和TSPYL5过表达+化学缺氧组,采用流式细胞仪检测凋亡率,Western blot检测活化胱天蛋白酶-3
Abstract:
Objective:To investigate the role and mechanism of testis-specific Y-encoded-like protein 5(TSPYL5)in myocardial ischemia injury.Methods:The myocardial ischemia model of mice was established. The expression level of TSPYL5 in myocardial tissue of m

参考文献/References

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备注/Memo

备注/Memo:
基金项目:
通信作者:黄日太,E-mail:huangritai@renji.com
更新日期/Last Update: 2021-08-15