文章摘要

参考文献/References

[1] 王文, 隋辉, 陈伟伟. 《中国高血压基层管理指南》要点解读[J]. 心脑血管病防治, 2015, 30(6):439-442.
[2] Partch CL, Green CB, Takahashi JS, et al. Molecular architecture of the mammalian circadian clock[J]. Trends Cell Biol, 2014, 24(2):90-99.
[3] Majumdar T, Dhar J, Patel S, et al. Circadian transcription factor BMAL1 regulates innate immunity against select RNA viruses[J]. Innate Immun, 2017, 23(2):147-154.
[4] 王洪云, 郭宏兴, 张吉翔. Bmal1基因与衰老的关系[J]. 生命的化学, 2007, 27(4):67-69.
[5] Trott AJ, Menet JS. Regulation of circadian clock transcriptional output by CLOCK: BMAL1[J]. PLoS Genet, 2018, 14(1):e1007156.
[6] Woon PY, Kaisaki PJ, Bragança J, et al. Aryl hydrocarbon receptor nuclear translocator-like(BMAL1)is associated with susceptibility to hypertension and type 2 diabetes[J]. Proc Natl Acad Sci U S A, 2007, 104(36):14412-14417.
[7] Huang J, Sabater-Lleal M, Asselbergs FW, et al. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation[J]. Blood, 2012, 120(24):4873-4881.
[8] Leu HB, ChungCM, Lin SJ, et al. Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension[J]. Hypertens Res, 2015, 38(2):155-162.
[9] Reppert SM, Weaver DR. Molecular analysis of mammalian circadian rhythms[J]. Annu Rev Physiol, 2001, 63(1):647-676.
[10] Xie Z, Su W, Liu S, et al. Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation[J]. J Clin Invest, 2015, 125(1):324-336.
[11] Chang L, Xiong W, Zhao X, et al. Bmal1 in perivascular adipose tissue regulates resting-phase blood pressure through transcriptional regulation of angiotensinogen[J]. Circulation, 2018, 138(1):67-79.
[12] Zhang D, Pollock DM. Circadian regulation of kidney function: finding a role for Bmal1[J]. Am J Physiol Renal Physiol, 2018, 314(5):F675-F678.
[13] Anea CB, Cheng B, Sharma S, et al. Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice[J]. Circ Res, 2012, 111(9):1157-1165.
[14] Anea CB, Zhang M, Chen F, et al. Circadian clock control of Nox4 and reactive oxygen species in the vasculature[J]. PLoS One, 2013, 8(10):e78626.
[15] Curtis AM, Cheng Y, Kapoor S, et al. Circadian variation of blood pressure and the vascular response to asynchronous stress[J]. Proc Natl Acad Sci U S A, 2007, 104(9):3450-3455.
[16] Marcheva B, Ramsey KM, Buhr ED, et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes[J]. Nature, 2010, 466(7306):627-631.
[17] Lutshumba J, Liu S, Zhong Y, et al. Deletion of BMAL1 in smooth muscle cells protects mice from abdominal aortic aneurysms[J]. Arterioscler Thromb Vasc Biol, 2018, 38(5):1063-1075.
[18] Shang X, Pati P, Anea CB, et al. Differential regulation of BMAL1, CLOCK, and endothelial signalling in the aortic arch and ligated common carotid artery[J]. J Vasc Res, 2016, 53(5/6):269-278.
[19] 胡义秋, 谢光荣. CLOCK基因的结构、变异及其表达[J]. 国际精神病学杂志, 2010, 37(2):49-51.
[20] Katzenberg D, Young T, Finn L, et al. A clock polymorphismassociated with human diurnal preference[J]. Sleep, 1998, 21(6):569-576.
[21] Mishima K, Tozawa T, Satoh K, et al. The 3111T/C polymorphism of hClock is associated with evening preference and delayed sleep timing in a Japanese population sample[J]. Am J Med Genet B Neuropsychiatr Genet, 2005, 133B(1):101-104.
[22] Bandín C, Martinez-Nicolas A, Ordovás JM, et al. Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position[J]. Int J Obes(Lond), 2013, 37(8):1044-1050.
[23] Turek FW, Joshu C, Kohsaka A, et al. Obesity and metabolic syndrome in circadian Clock mutant mice[J]. Science, 2005, 308(5724):1043-1045.
[24] Durgan DJ, Young ME. The cardiomyocyte circadian clock: emerging roles in health and disease[J]. Circ Res, 2010, 106(4):647-658.
[25] Zuber AM, Centeno G, Pradervand S, et al. Molecular clock is involved in predictive circadian adjustment of renal function[J]. Proc Natl Acad Sci U S A, 2009, 106(38):16523-16528.
[26] Nakashima A, Kawamoto T, Noshiro M, et al. Dec1 and CLOCK regulate Na⁺/K⁺-ATPase β1 subunit expression and blood pressure[J]. Hypertension, 2018, 72(3):746-754.
[27] Zhou M, Kim JK, Eng GW, et al. A Period2 phosphoswitch regulates and temperature compensates circadian period[J]. Mol Cell, 2015, 60(1):77-88.
[28] Pati P, Fulton DJ, Bagi Z, et al. Low-salt diet and circadian dysfunction synergize to induce angiotensin Ⅱ-dependent hypertension in mice[J]. Hypertension, 2016, 67(3):661-668.
[29] Solocinski K, Holzworth M, Wen X, et al. Desoxycorticosterone pivalate-salt treatment leads to non-dipping hypertension in Per1 knockout mice[J]. Acta Physiol(Oxf), 2017, 220(1):72-82.
[30] Douma LG, Holzworth MR, Solocinski K, et al. Renal Na-handling defect associated with PER1-dependent nondipping hypertension in male mice[J]. Am J Physiol Renal Physiol, 2018, 314(6):F1138-F1144.
[31] Douma LG, Solocinski K, Holzworth MR, et al. Female C57BL/6J mice lacking the circadian clock protein PER1 are protected from nondipping hypertension[J]. Am J Physiol Regul Integr Comp Physiol, 2019, 316(1):R50-R58.
[32] Richards J, Ko B, All S, et al. A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter(NCC)and the with-no-lysine kinase(WNK)cascade in mouse distal convoluted tubule cells[J]. J Biol Chem, 2014, 289(17):11791-11806.
[33] Hernandez ME, Watkins JM, Vu J, et al. DOCA/salt hypertension alters Period1 and orexin-related gene expression in the medulla and hypothalamus of male rats: diurnal influences[J]. Auton Neurosci, 2018, 210:34-43.
[34] Richards J, Welch AK, Barilovits SJ, et al. Tissue-specific and time-dependent regulation of the endothelin axis by the circadian clock protein Per1[J]. Life Sci, 2014, 118(2):255-262.
[35] Stow LR, Richards J, Cheng KY, et al. The circadian protein period 1 contributes to blood pressure control and coordinately regulates renal sodium transport genes[J]. Hypertension, 2012, 59(6):1151-1156.
[36] Sakamoto S, Miyazaki K, Fukui H, et al. Molecular characterization and nuclear localization of rat timeless-like gene product[J]. Biochem Biophys Res Commun, 2000, 279(1):131-138.
[37] Hou T, Su W, Guo Z, et al. A novel diabetic mouse model for real-time monitoring of clock gene oscillation and blood pressure circadian rhythm[J]. J Biol Rhythms, 2019, 34(1):51-68.
[38] Oishi K, Miyazaki K, Uchida D, et al. PERIOD2 is a circadian negative regulator of PAI-1 gene expression in mice[J]. J Mol Cell Cardiol, 2009, 46(4):545-552.
[39] Wang CY, Wen MS, Wang HW, et al. Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2[J]. Circulation, 2008, 118(21):2166-2173.
[40] Eckle T, Hartmann K, Bonney S, et al. Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia[J]. Nat Med, 2012, 18(5):774-782.
[41] 安怀杰, 郑巍薇, 史成和, 等. 生物钟基因period3的多态性及其与睡眠关系的研究进展[J]. 山西医科大学学报, 2014, 45(6):525-528.
[42] Lipkova J, Splichal Z, Bienertova-Vasku JA, et al. Period3 VNTR polymorphism influences the time-of-day pain onset of acute myocardial infarction with ST elevation[J]. Chronobiol Int, 2014, 31(8):878-890.
[43] Dijk DJ, Archer SN. PERIOD3, circadian phenotypes, and sleep homeostasis[J]. Sleep Med Rev, 2010, 14(3):151-160.
[44] Viola AU, James LM, Archer SN, et al. PER3 polymorphism and cardiac autonomic control: effects of sleep debt and circadian phase[J]. Am J Physiol Heart Circ Physiol, 2008, 295(5):H2156-H2163.
[45] Yang MY, Lin PW, Lin HC, et al. Alternations of circadian clock genes expression and oscillation in obstructive sleep apnea[J]. J Clin Med, 2019, 8(10):1634.
[46] Lipkova J, Bienertova-Vasku JA, Spinarova L, et al. Per3 VNTR polymorphism and chronic heart failure[J]. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2014, 158(1):80-83.
[47] Khan SK, Xu H, Ukai-Tadenuma M, et al. Identification of a novel cryptochrome differentiating domain required for feedback repression in circadian clock function[J]. J Biol Chem, 2012, 287(31):25917-25926.
[48] Richards J, Cheng KY, All S, et al. A role for the circadian clock protein Per1 in the regulation of aldosterone levels and renal Na⁺ retention[J]. Am J Physiol Renal Physiol, 2013, 305(12):F1697-F1704.
[49] Doi M, Takahashi Y, Komatsu R, et al. Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6[J]. Nat Med, 2010, 16(1):67-74.
[50] Okamura H, Doi M, Goto K, et al. Clock genes and salt-sensitive hypertension: a new type of aldosterone-synthesizing enzyme controlled by the circadian clock and angiotensin Ⅱ[J]. Hypertens Res, 2016, 39(10):681-687.
[51] Masuki S, Todo T, Nakano Y, et al. Reduced alpha-adrenoceptor responsiveness and enhanced baroreflex sensitivity in Cry-deficient mice lacking a biological clock[J]. J Physiol, 2005, 566(Pt 1):213-224.
[52] Nugrahaningsih DA, Emoto N, Vignon-Zellweger N, et al. Chronic hyperaldosteronism in cryptochrome-null mice induces high-salt- and blood pressure-independent kidney damage in mice[J]. Hypertens Res, 2014, 37(3):202-209.
[53] Tanida M, Yamatodani A, Niijima A, et al. Autonomic and cardiovascular responses to scent stimulation are altered in cry KO mice[J]. Neurosci Lett, 2007, 413(2):177-182.
[54] Hirota T, Lee JW, St John PC, et al. Identification of small molecule activators of cryptochrome[J]. Science, 2012, 337(6098):1094-1097.

[1]王欣婷袁晓晨.生物钟相关基因参与高血压的机制[J].国际心血管病杂志,2020,05:285-289.

点击复制

生物钟相关基因参与高血压的机制(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

文章信息/Info

参考文献/References

备注/Memo

常用功能

导航/Navigate

工具/Tools

统计/Statistics

[1]王欣婷 袁晓晨.生物钟相关基因参与高血压的机制[J].国际心血管病杂志,2020,05:285-289. 点击复制 生物钟相关基因参与高血压的机制(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

文章信息/Info

参考文献/References

备注/Memo

常用功能

导航/Navigate

工具/Tools

统计/Statistics

[1]王欣婷袁晓晨.生物钟相关基因参与高血压的机制[J].国际心血管病杂志,2020,05:285-289.

点击复制

生物钟相关基因参与高血压的机制(PDF)