索引超出了数组界限。 文章摘要
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[1]杜胜利 范一帆 钟久昌 王乐丰.Kruppel样因子15在冠状动脉粥样硬化性心脏病中的作用[J].国际心血管病杂志,2020,05:276-280.
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Kruppel样因子15在冠状动脉粥样硬化性心脏病中的作用(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2020年05期
页码:
276-280
栏目:
综述
出版日期:
2020-10-15

文章信息/Info

Title:
-
作者:
杜胜利 范一帆 钟久昌 王乐丰
100020 首都医科大学附属北京朝阳医院
Author(s):
-
关键词:
冠状动脉粥样硬化性心脏病;  Kruppel样因子15;  心肌缺血;  血管重构
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2020.05.006
文献标识码:
-
摘要:
Kruppel样因子(KLF)15是KLF家族的一个亚型,能够调节细胞增殖、分化、发育和凋亡等生物学过程。在心血管系统,KLF15具有调控糖脂代谢、改善血管壁重构、减轻心肌细胞炎性反应及缺血再灌注损伤等作用。该文主要介绍KLF15在冠状动脉粥样硬化性心脏病中的作用。
Abstract:
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参考文献/References

[1] Pei J, Grishin NV. A new family of predicted Kruppel-like factor genes and pseudogenes in placental mammals[J]. PLoS One, 2013, 8(11):e81109.
[2] Yoda T, McNamara KM, Miki Y, et al. KLF15 in breast cancer: a novel tumor suppressor?[J]. Cell Oncol(Dordr), 2015, 38(3):227-235.
[3] Prosdocimo DA, Sabeh MK, Jain MK. Kruppel-like factors in muscle health and disease[J]. Trends Cardiovasc Med, 2015, 25(4):278-287.
[4] Pandey D, Nomura Y, Rossberg MC, et al. Hypoxia triggers SENP1(sentrin-specific protease 1)modulation of KLF15(Kruppel-like factor 15)and transcriptional regulation of Arg2(Arginase 2)in pulmonary endothelium[J]. Arterioscler Thromb Vasc Biol, 2018, 38(4):913-926.
[5] Bing L, Lili X, Xinming Y, et al. Protective effect of KLF15 on vascular endothelial dysfunction induced by TNF-α[J]. Mol Med Rep, 2018, 18(2):1987-1994.
[6] Alaiti MA, Orasanu G, Tugal D, et al. Kruppel-like factors and vascular inflammation: implications for atherosclerosis[J]. Curr Atheroscler Rep, 2012, 14(5):438-449.
[7] Raines EW. PDGF and cardiovascular disease[J]. Cytokine Growth Factor Rev, 2004, 15(4):237-254.
[8] Lu Y, Haldar S, Croce K, et al. Kruppel-like factor 15 regulates smooth muscle response to vascular injury—brief report[J]. Arterioscler Thromb Vasc Biol, 2010, 30(8):1550-1552.
[9] Lu Y, Zhang L, Liao X, et al. Kruppel-like factor 15 is critical for vascular inflammation[J]. J Clin Invest, 2013,123(10):4232-4241.
[10] Abe J, Berk BC. Novel mechanisms of endothelial mechanotransduction[J]. Arterioscler Thromb Vasc Biol, 2014, 34(11):2378-2386.
[11] Jiang J, Xia Y, Liang Y, et al. miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension[J]. Int J Chron Obstruct Pulmon Dis, 2018, 13:3777-3790.
[12] Gu X, Mallipattu SK, Guo Y, et al. The loss of Kruppel-like factor 15 in Foxd1(+)stromal cells exacerbates kidney fibrosis[J]. Kidney Int, 2017, 92(5):1178-1193.
[13] Lu YY, Li XD, Zhou HD, et al. Transactivation domain of Kruppel-like factor 15 negatively regulates angiotensin Ⅱ-induced adventitial inflammation and fibrosis[J]. FASEB J, 2019, 33(5):6254-6268.
[14] Mihailidou A, Ashton A. Os 15-04 mineralocorticoid receptor antagonists target endogenous repressor of hypertrophy[J]. J Hypertens, 2016, 34:e215-e216.
[15] 余杨, 邹书帆, 马杰, 等. kruppel样因子15在压力超负荷所致心肌重构血管生成中的作用及机制[J]. 中华心血管病杂志, 2015, 43(2):162-166.
[16] Gallo A, Vannier C, Galli T. Endoplasmic reticulum-plasma membrane associations: structures and functions[J]. Annu Rev Cell Dev Biol, 2016, 32(1):279-301.
[17] Jung DY, Chalasani U, Pan N, et al. KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance[J]. PLoS ONE, 2013, 8(10):e77851.
[18] Zhou L, Li Q, Chen A, et al. KLF15-activating Twist2 ameliorated hepatic steatosis by inhibiting inflammation and improving mitochondrial dysfunction via NF-kappaB-FGF21 or SREBP1c-FGF21 pathway[J]. FASEB J, 2019, 33(12):14254-14269.
[19] Tang Q, Li MY, Su YF, et al. Absence of miR-223-3p ameliorates hypoxia-induced injury through repressing cardiomyocyte apoptosis and oxidative stress by targeting KLF15[J]. Eur J Pharmacol, 2018, 84(1):67-74.
[20] Zhao T, Qiu Z, Gao Y. MiR-137-3p exacerbates the ischemia-reperfusion injured cardiomyocyte apoptosis by targeting KLF15[J]. Naunyn Schmiedebergs Arch Pharmacol, 2020, 393(6):1013-1024.
[21] Rogers RG, Otis JS. Resveratrol-mediated expression of KLF15 in the ischemic myocardium is associated with an improved cardiac phenotype[J]. Cardiovasc Drugs Ther, 2017, 31(1):29-38.
[22] Wang B, Haldar SM, Lu Y, et al. The Kruppel-like factor KLF15 inhibits connective tissue growth factor(CTGF)expression in cardiac fibroblasts[J]. J Mol Cell Cardiol, 2008, 45(2):193-197.
[23] Noack C, Zafiriou MP, Schaeffer HJ, et al. Krueppel-like factor 15 regulates Wnt/β-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart[J]. EMBO Mol Med, 2012, 4(9):992-1007.
[24] Zhang L, Prosdocimo DA, Bai X, et al. KLF15 establishes the landscape of diurnal expression in the heart[J]. Cell Rep, 2015, 13(11):2368-2375.
[25] Jeyaraj D, Haldar SM, Wan X, et al. Circadian rhythms govern cardiac repolarization and arrhythmogenesis[J]. Nature, 2012, 483(7387):96-99.
[26] Fei Z, Bera TK, Liu X, et al. Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblasts[J]. J Biol Chem, 2011, 286(31):27761-27768.
[27] Yamamoto J, Ikeda Y, Iguchi H, et al. A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2[J]. J Biol Chem, 2004, 279(17):16954-16962.
[28] Prosdocimo DA, Anand P, Liao X, et al. Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism[J]. J Biol Chem, 2014, 289(9):5914-5924.
[29] Prosdocimo DA, John JE, Zhang L, et al. KLF15 and PPARα cooperate to regulate cardiomyocyte lipid gene expression and oxidation[J]. PPAR Res, 2015, 2015:201625.
[30] Wang C, Ha X, Li W, et al. Correlation of A2bAR and KLF4/KLF15 with obesity-dyslipidemia induced inflammation in Uygur population[J]. Mediators Inflamm, 2016, 2016(6):7015620.
[31] Zhang J, Zhong HB, Lin Y, et al. KLF15 suppresses cell proliferation and extracellular matrix expression in mesangial cells under high glucose[J]. Int J Clin Exp Med, 2016, 8(11):20330-20336.
[32] Fan L, Hsieh PN, Sweet DR, et al. Krüppel-like factor 15: regulator of BCAA metabolism and circadian protein rhythmicity[J]. Pharmacol Res, 2018, 130(4):123-126.
[33] Takeuchi Y, Yahagi N, Aita Y, et al. KLF15 enables rapid switching between lipogenesis and gluconeogenesis during fasting[J]. Cell Rep, 2016, 16(9):2373-2386.
[34] Nagare T, Sakaue H, Matsumoto M, et al. Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion[J]. J Biol Chem, 2011, 286(43):37458-37469.
[35] Teshigawara K, Ogawa W, Mori T, et al. Role of Kruppel-like factor 15 in PEPCK gene expression in the liver[J]. Biochem Biophys Res Commun, 2005, 327(3):920-926.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81770253,81370362)
通信作者:王乐丰,E-mail:wlf20182021@163.com
更新日期/Last Update: 2020-10-15