|本期目录/Table of Contents|

[1]李月亮 张国奇 林海利.血清可溶性信号素4D水平与急性ST段抬高型心肌梗死患者近期预后的相关性[J].国际心血管病杂志,2020,01:55-58.
　LI Yueliang,ZHANG Guoqi,LIN Haili.Association between Sema4D level and short-term prognosis in patients with acute ST-segment elevation myocardial infarction[J].International Journal of Cardiovascular Disease,2020,01:55-58.
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血清可溶性信号素4D水平与急性ST段抬高型心肌梗死患者近期预后的相关性(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2020年01期
页码:
55-58
栏目:
临床研究
出版日期:
2020-01-14

文章信息/Info

Title:
Association between Sema4D level and short-term prognosis in patients with acute ST-segment elevation myocardial infarction
作者:
李月亮 张国奇 林海利
511518广州医科大学附属第六医院清远市人民医院心血管内科一区
Author(s):
LI Yueliang;  ZHANG Guoqi;  LIN Haili
Department of Cardiology, Sixth Hospital Affiliated to Guangzhou Medical University, Qingyuan People's Hospital, Guangdong511518, China
关键词:
急性ST段抬高型心肌梗死;  信号素4D;  预后;  心血管不良事件
Keywords:
Acute ST-segment elevation myocardial infarction;  Semaphorin 4D;  Prognosis;  Cardiovascular adverse events
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2020.01.014
文献标识码:
-
摘要:
目的:观察分析血清可溶性信号素4D(Sema4D)水平与急性ST段抬高型心肌梗死(STEMI)患者近期预后的相关性。方法:选取2017年6月至2018年6月收治的100例接受经皮冠状动脉介入术(PCI)的STEMI患者,依据基线血清Sema4D中位数水平,将患者分为Sema4D低值组(≤9.14 ng/mL)57例和Sema4D高值组(>9.14 ng/mL)43例。收集两组一般资料,比较两组随访期间心血管不良事件发生率,分析预后影响因素。结果:Sema4D低值组的收缩压和左室射血分数均高于Sema4D高值组(P<0.05); Sema4D高值组心血管不良事件发生率明显高于Sema4D低值组(P<0.05); Sema4D>9.14 ng/mL、左室射血分数是影响STEMI患者预后的独立危险因素(P<0.05)。结论:血清可溶性Sema4D水平升高对行PCI的STEMI患者预后具有重要预测价值。
Abstract:
Objective:To investigate the relationship between serum soluble semaphorin 4D(Sema4D)level and short-term prognosis in patients with acute ST-segment elevation myocardial infarction(STEMI).Methods:From June 2017 to June 2018, one hundred patients with STEMI undergonging percutaneous coronary intervention in our hospital were included. According to the median serum soluble Sema4D level, the enrolled patients were divided into low value Sema4D group(≤9.14 ng/mL, n=57)and high value Sema4D group(>9.14 ng/mL, n=43). The general data of all the patients were collected. The incidence of cardiovascular adverse events during the follow-up period were compared between the two groups, and the prognostic factors were analyzed. Results:Compared with the low value Sema4D group, the high value Sema4D group suffered higher incidence of cardiovascular adverse events, with lower systolic blood pressure and left ventricular ejection fraction(P<0.05). Sema4D>9.14 ng/mL, left ventricular ejection fraction were independent risk factors for prognosis in patients with STEMI(P<0.05).Conclusions:Elevated serum soluble Sema4D level has important predictive value for the prognosis of patients with STEMI undergoing PCI.

参考文献/References

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备注/Memo

备注/Memo:
基金项目:清远市科技计划(180612201900178)
作者单位:511518广州医科大学附属第六医院清远市人民医院心血管内科一区
通信作者:李月亮,E-mail:lizchong@163.com
更新日期/Last Update: 2020-01-15