索引超出了数组界限。 文章摘要
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[1]成彪 高凌云.氧化三甲胺与急性冠脉综合征的研究进展[J].国际心血管病杂志,2019,04:216-218.
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氧化三甲胺与急性冠脉综合征的研究进展(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2019年04期
页码:
216-218
栏目:
综述
出版日期:
2019-09-27

文章信息/Info

Title:
-
作者:
成彪 高凌云
400016 重庆医科大学研究生院(成彪); 400016 重庆医科大学附属第一医院心血管内科(高凌云)
Author(s):
-
关键词:
氧化三甲胺;  急性冠脉综合征;  动脉粥样硬化
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2019.04.007
文献标识码:
-
摘要:
血浆氧化三甲胺(TMAO)水平对心血管疾病不良事件有预测作用,该文主要介绍TMAO与急性冠脉综合征的研究进展。
Abstract:
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参考文献/References

[ 1 ] Wang Z, Klipfell E, Bennett BJ, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease[J].Nature, 2011, 472(7341):57-63.
[ 2 ] Tang WH, Wang Z, Levison BS, et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk[J].N Engl J Med, 2013,368(17):1575-1584.
[ 3 ] Koeth RA, Wang Z, Levison BS, et al. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis[J].Nat Med, 2013,19(5):576-585.
[ 4 ] Bennett BJ, de Aguiar Vallim TQ, Wang Z, et al. Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation[J].Cell Metab, 2013,17(1):49-60.
[ 5 ] Hartiala J, Bennett BJ, Tang WH, et al. Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine[J].Arterioscler Thromb Vasc Biol, 2014, 34(6):1307-1313.
[ 6 ] 王珊, 夏耿红, 何彦, 等. 氧化三甲胺分布特征及其与肠道菌群的关联性[J]. 南方医科大学, 2016, 36(4):455-460.
[ 7 ] Nowiński A, Ufnal M. Trimethylamine N-oxide: a harmful, protective or diagnostic marker in lifestyle diseases?[J].Nutrition, 2018,46:7-12.
[ 8 ] Subramaniam S, Fletcher C. Trimethylamine N-oxide: breathe new life[J].Br J Pharmacol, 2018,175(8):1344-1353.
[ 9 ] Heianza Y, Ma W, Manson JE, et al. Gut microbiota metabolites and risk of major adverse cardiovascular disease events and death: a systematic review and meta-analysis of prospective studies[J].J Am Heart Assoc, 2017, 6(7):e004947.
[10] Li XS, Obeid S, Klingenberg R, et al. Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors[J]. Eur Heart J, 2017, 38(11):814-824.
[11] Liu X, Xie Z, Sun M, et al. Plasma trimethylamine N-oxide is associated with vulnerable plaque characteristics in CAD patients as assessed by optical coherence tomography[J]. Int J Cardiol, 2018, 265:18-23.
[12] Meyer KA, Benton TZ, Bennett BJ, et al. Microbiota-Dependent metabolite trimethylamine N-oxide and coronary artery calcium in the coronary artery risk development in young adults study(CARDIA)[J]. J Am Heart Assoc, 2016, 5(10):e003970.
[13] Senthong V, Li XS, Hudec T, et al. Plasma trimethylamine N-oxide, a gut microbe-generated phosphatidylcholine metabolite, is associated with atherosclerotic burden[J]. J Am Coll Cardiol, 2016, 67(22):2620-2628.
[14] Velasquez MT, Ramezani A, Manal A, et al. Trimethylamine N-oxide: the good, the bad and the unknown[J].Toxins(Basel), 2016, 8(11):e326.
[15] Zong C, Yu Y, Song G, et al. Chitosan oligosaccharides promote reverse cholesterol transport and expression of scavenger receptor BI and CYP7A1 in mice[J].Exp Biol Med(Maywood), 2012, 237(2):194-200.
[16] Li T,Chen Y,Gua C,et al.Elevated circulating trimethylamine N-oxide levels contribute to endothelial dysfunction in aged rats through vascular inflammation and oxidative stress[J].Front Physiol, 2017, 8:350.
[17] Ma G,Pan B,Chen Y,et al.Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion[J].Biosci Rep, 2017,37(2):BSR20160244.
[18] Seldin MM. Meng Y, Qi H, et al. Trimethylamine N-Oxide promotes vascular inflammation through signaling of mitogen-activated protein kinase and nuclear factor-κB[J]. J Am Heart Assoc, 2016, 5(2):e002767.
[19] Sun X, Jiao X, Ma Y, et al.Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical vein endothelial cells via activating ROS-TXNIP-NLRP3 inflammasome[J].Biochem Biophys Res Commun, 2016, 481(1-2):63-70.
[20] Zhu W, Gregory JC, Org E, et al. Gut microbial metabolite of TMAO enhances platelet hyperreactivity and thrombosis risk[J]. Cell, 2016, 165(1):111-124.
[21] Wang Z, Roberts AB, Buffa JA, et al. Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis[J]. Cell, 2015, 163(7):1585-1595.
[22] Chen ML,Yi L,Zhang Y,et al.Resveratrol attenuates trimethylamine-N-oxide(TMAO)-induced atherosclerosis by regulating TMAO synthesis and bile acid metabolism via remodeling of the gut microbiota[J].MBio, 2016, 7(2): e02210-e02215.
[23] Lyu M, Wang YF, Fan GW, et al. Balancing herbal medicine and functional food for prevention and treatment of cardiometabolic diseases through modulating gut microbiota[J].Front Microbiol, 2017, 8:2146.
[24] Yamashita T, Kasahara K, Emoto T, et al. Intestinal immunity and gut microbiota as therapeutic targets for preventing atherosclerotic cardiovascular diseases[J]. Circ J, 2015, 79(9):1882-1890.
[25] Yamashita T. Intestinal immunity and gut microbiota in atherogenesis[J].J Atheroscler Thromb, 2017, 24(2): 110-119.
[26] Zhu W, Wang Z, Tang WHW, et al. Gut microbe-generated trimethylamine N-oxide from dietary choline is prothrombotic in subjects[J]. Circulation, 2017, 135(17):1671-1673.

备注/Memo

备注/Memo:

作者单位:400016 重庆医科大学研究生院(成彪); 400016 重庆医科大学附属第一医院心血管内科(高凌云)
通信作者:高凌云,Email:806841801@qq.com
更新日期/Last Update: 2019-09-27