|本期目录/Table of Contents|

[1]赵普庆,刘欣燕,贾维,等.高血压合并阻塞性睡眠呼吸暂停患者血清胱抑素C的危险因素[J].国际心血管病杂志,2016,06:383-386.
 ZHAO Puqing,LIU Xinyan,JIA Wei,et al.Risk factors of serum cystatin C in hypertensive patients with obstructive sleep apnea[J].International Journal of Cardiovascular Disease,2016,06:383-386.
点击复制

高血压合并阻塞性睡眠呼吸暂停患者血清胱抑素C的危险因素(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2016年06期
页码:
383-386
栏目:
临床研究
出版日期:
2016-11-20

文章信息/Info

Title:
Risk factors of serum cystatin C in hypertensive patients with obstructive sleep apnea
作者:
赵普庆刘欣燕贾维董斌斌杨沁彤吴诚
200082 上海中医药大学附属上海市中西医结合医院呼吸内科(赵普庆,贾 维,吴 诚); 科研处(刘欣燕); 脉管科(杨沁彤); 201907 上海,复旦大学附属华山医院北院儿科(董斌斌)
Author(s):
ZHAO Puqing1 LIU Xinyan2 JIA Wei1 DONG Bingbing3 YANG Qintong4 WU Cheng1.
1.Department of Respiratory; 2.Department of Scientific Research, Shanghai Traditional Chinese Medicine Integrated Hospital, Shanghai Traditional Chinese Medicine University, Shanghai 200082; 3.Department of Pediatrics, North Hospital of Huashan Hospital
关键词:
阻塞性睡眠呼吸暂停高血压血清胱抑素夜间缺氧危险因素
Keywords:
Obstructive sleep apnea Hypertension Serum cystatin C Nocturnal hypoxia Risk factor
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2016.06.017
文献标识码:
-
摘要:
目的:探讨高血压合并阻塞性睡眠呼吸暂停(obstructivesleepapnea,OSA)患者血清胱抑素(CysC)的危险因素。方法:83例高血压患者行血生化和多导睡眠仪检测,根据多导睡眠仪的监测结果,符合OSA诊断的41例患者作为高血压合并OSA组,42例单纯高血压患者作为高血压组。结果:(1)高血压合并OSA组的体质量、体质量指数、颈围、腰围、腰臀比、收缩压、夜间缺氧事件总数、夜间缺氧事件总时间、睡眠呼吸暂停低通气指数(AHI)、空腹血糖、餐后2h血糖、CysC、总胆固醇、三酰甘油和低密度脂蛋白胆固
Abstract:
Objective:To investigate the risk factor of serum cystatin C in hypertensive patients with obstructive sleep apnea.Methods: According to the results of polysomnograph(PSG), eighty-three hypertensive patients were divided into two groups: hypertension with

参考文献/References

[1] Somers VK, White DP, Amin R, et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardliology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing[J]. Circulation, 2008, 118(10):1080-1111.
[2] 睡眠呼吸暂停与心血管疾病专家共识组.睡眠呼吸暂停与心血管疾病专家共识[J].中华内科杂志, 2009, 48(12):1059-1067.
[3] 赵普庆,邓 兵. 阻塞性睡眠呼吸暂停促进高血压发生的机制[J]. 国际心血管病杂志, 2011, 38(3):163-166.
[4] 赵普庆,邓 兵,艾自胜,等.高血压合并阻塞性睡眠呼吸暂停患者发生颈动脉粥样硬化的危险因素[J].上海医学, 2012, 35(6):877-880.
[5] Mussap M, Plebani M. Biochemistry and clinical role of human cystatin C[J]. Crit Rev Clin Lab Sci, 2004, 41(5-6):467-550.
[6] Salgado JV, Souza FL, Salgado BJ. How to understand the association between cystatin C levels and cardiovascular disease:Imbalance,counterbalance,or consequence?[J]. J Cardiol, 2013,62(6):331-335.
[7] Evangelopoulos AA,Vallianou NG, Bountziouka V, et al. Association between serum cystatin C, monocytes and other inflammatory markers[J]. Intern Med, 2012,42(5):517-522.
[8] 赵普庆,邓 兵,毛 玉,等.高血压合并阻塞性睡眠呼吸暂停综合征动态血压临床分析[J].国际心血管病杂志, 2011, 38(4):253-256.
[9] 赵普庆,邓 兵,艾自胜,等. 高血压合并阻塞性睡眠呼吸暂停患者胰岛素抵抗临床分析[J].国际心血管病杂志, 2012, 39(4):251-254.
[10] 赵普庆,邓 兵,艾自胜,等. 高血压合并阻塞性睡眠呼吸暂停患者夜间缺氧与外部形态特征关系[J]. 同济大学学报(医学版), 2011,32(6):95-99.
[11] Zhang XB, Lin QC, Deng CS, et al. Elevated serum cystatin C in severe OSA younger men without complications[J]. Sleep Breath, 2013,17(1): 235-241.
[12] Kato K, Takata Y, Usui Y, et al. Severe obstructive sleep apnea increases cystatin C in clinically latent renal dysfunction[J]. Respiratory Med, 2011,105(4): 643-649.
[13] 李 莉,余 勤.阻塞性睡眠呼吸暂停低通气综合征患者血清胱蛋白酶抑制剂C水平及尿系列酶活性的变化[J].中国呼吸与危重监护杂志, 2006, 5(5): 366-369.
[14] 侯婷婷,周 川,谢 萍,等. 阻塞性睡眠呼吸暂停低通气综合征相关性高血压患者血清胱抑素C和超氧化物歧化酶水平的变化[J].中国循环杂志, 2016, 31(5): 463-466.

备注/Memo

备注/Memo:
基金项目:上海市卫生和计划生育委员会科研课题(201640098) 作者单位:200082 上海中医药大学附属上海市中西医结合医院呼吸内科(赵普庆,贾 维,吴 诚); 科研处(刘欣燕); 脉管科(杨沁彤); 201907 上海,复旦大学附属华山医院北院儿科(董斌斌) 通信作者:贾 维,Email:jia11wei11@sina.com
更新日期/Last Update: 2016-11-20