索引超出了数组界限。 文章摘要
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[1]郑芳芳,朱理敏,高平进.体细胞突变在醛固酮腺瘤发病中的作用[J].国际心血管病杂志,2016,01:39-42.
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体细胞突变在醛固酮腺瘤发病中的作用(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2016年01期
页码:
39-42
栏目:
综述
出版日期:
2016-01-20

文章信息/Info

Title:
-
作者:
郑芳芳; 朱理敏; 高平进
200025 上海交通大学医学院附属瑞金医院高血压科,上海市高血压研究所
Author(s):
-
关键词:
体细胞突变; 原发性醛固酮增多症; 醛固酮腺瘤; 离子通道
Keywords:
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分类号:
-
DOI:
10.3969/j.issn.1673-6583.2016.01.012
文献标识码:
-
摘要:
原发性醛固酮增多症是继发性高血压的常见病因,可导致严重的心脑血管病变,影响患者预后。KCNJ5、ATP1A1、ATP2B3和CACNA1D基因体细胞突变通过影响不同的离子稳态,增加细胞内钙离子浓度,从而刺激肾上腺皮质球状带细胞分泌过多的醛固酮。该文主要介绍醛固酮腺瘤发病中上述基因体细胞突变的作用。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金青年项目(81500324) 作者单位:200025 上海交通大学医学院附属瑞金医院高血压科,上海市高血压研究所 通信作者:高平进,Email:gaopingjin@sibs.ac.cn
更新日期/Last Update: 2016-01-20