|本期目录/Table of Contents|

[1]贾静,何江波,曾韦锟,等.外源性硫化氢对心肌肥大的保护作用[J].国际心血管病杂志,2015,06:403-406.
　JIA Jing,HE Jiangbo,ZENG Weikun,et al.Protective effect of exogenous hydrogen sulfide on myocardial hypertrophy[J].International Journal of Cardiovascular Disease,2015,06:403-406.
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外源性硫化氢对心肌肥大的保护作用(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2015年06期
页码:
403-406
栏目:
出版日期:
2015-11-25

文章信息/Info

Title:
Protective effect of exogenous hydrogen sulfide on myocardial hypertrophy
作者:
贾静; 何江波; 曾韦锟; 余珊; 王波; 陶剑; 俞华; 李军
650214 昆明学院医学院
Author(s):
JIA Jing;  HE Jiangbo; ZENG Weikun;  YU Shan;  WANG Bo; TAO Jian;  YU Hua;  LI Jun.
Medical College, Kunming University, Kunming 650214, China
关键词:
硫化氢; 心肌肥大; 心肌细胞; 活性氧分子
Keywords:
Hydrogen sulfide;  Cardiac hypertrophy;  Cardiomyocytes;  Reactive oxygen species
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2015.06.010
文献标识码:
-
摘要:
目的:研究外源性硫化氢(H2S)对血管紧张素Ⅱ(AngⅡ)引起的心肌细胞肥大的保护作用。方法:将1～3日龄Wistar乳鼠心肌细胞培养48h,随机分为正常对照组、AngⅡ组、硫氢化钠组(NaHS组),其中AngⅡ组和NaHS组的心肌细胞经AngⅡ干预48h制备心肌肥大细胞模型,通过鬼笔环肽染色判定模型成功。NaHS组在肥大基础上用NaHS干预48h。JC-1染色观察各组线粒体膜电位势能变化。Mitosox测定各组活性氧(ROS)水平。Westernblot检测心肌细胞相关蛋白表达水平
Abstract:
Objective: To study the protective effect of hydrogen sulfide(H2S)on cardiac hypertrophy.Methods: Ventricular cardiomyocytes of Wistar neonatal rat(1～3 days old)were incubated for 48 h, then divided into control group, angiotension Ⅱ(Ang Ⅱ)grou

参考文献/References

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备注/Memo

备注/Memo:
基金项目: 昆明学院自然科学基础、应用基础研究基金项目(XJL12030)
更新日期/Last Update: 2015-12-20