索引超出了数组界限。
[1] Buonafine M, Bonnard B, Jaisser F. Mineralocorticoid receptor and cardiovascular disease[J]. Am J Hypertens, 2018, 31(11):1165-1174.
[2] Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators[J].N Engl J Med, 1999, 341(10):709-717.
[3] Staessen J, Lijnen P, Fagard R, et al. Rise in plasma concentration of aldosterone during long-term angiotensin Ⅱ suppression[J]. J Endocrinol, 1981, 91(3):457-465.
[4] Brilla CG, Matsubara LS, Weber KT. Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension[J]. Am J Cardiol, 1993, 71(3):A12-A16.
[5] Ponikowski P, Voors AA, Anker SD, et al. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC[J]. Eur J Heart Fail, 2016, 18(8):891-975.
[6] Pitt B, Pfeffer MA, Assmann SF, et al. Spironolactone for heart failure with preserved ejection fraction[J]. N Engl J Med, 2014, 370(15):1383-1392.
[7] Swedberg K, Zannad F, McMurray JJV, et al. Eplerenone and atrial fibrillation in mild systolic heart failure: results from the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure) study[J]. J Am Coll Cardiol, 2012, 59(18):1598-1603.
[8] Ferreira JP, Lamiral Z, McMurray JJV, et al. Impact of insulin treatment on the effect of eplerenone: insights from the EMPHASIS-HF trial[J]. Circ Heart Fail, 2021, 14(6):e008075.
[9] Cook CS, Berry LM, Bible RH, et al. Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans[J]. Drug Metab Dispos, 2003, 31(11):1448-1455.
[10] Weinberger MH, Roniker B, Krause SL,et al. Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension[J]. Am J Hypertens, 2002, 15(8):709-716.
[11] Ito S, Itoh H, Rakugi H, et al. Antihypertensive effects and safety of esaxerenone in patients with moderate kidney dysfunction[J]. Hypertens Res, 2021, 44(5):489-497.
[12] Ito S, Itoh H, Rakugi H, et al. Efficacy and safety of esaxerenone (CS-3150) for the treatment of essential hypertension: a phase 2 randomized, placebo-controlled, double-blind study[J]. J Hum Hypertens, 2019, 33(7):542-551.
[13] Ito S, Itoh H, Rakugi H, et al. Double-Blind randomized phase 3 study comparing esaxerenone (CS-3150) and eplerenone in patients with essential hypertension (ESAX-HTN study)[J]. Hypertension, 2020, 75(1):51-58.
[14] Yamada M, Mendell J, Takakusa H, et al. Pharmacokinetics, metabolism, and excretion of [14C]esaxerenone, a novel mineralocorticoid receptor blocker in humans[J]. Drug Metab Dispos, 2019, 47(3):340-349.
[15] Iijima T, Katoh M, Takedomi K, et al. Discovery of apararenone(MT-3995)as a highly selective, potent, and novel nonsteroidal mineralocorticoid receptor antagonist[J]. J Med Chem, 2022, 65(12):8127-8143.
[16] Wada TKH, Inagaki M, Yoshinari T, et al. Apararenone in patients with diabetic nephropathy: results of a randomized, double-blind, placebo-controlled phase 2 dose-response study and open-label extension study[J]. Clin Exp Nephrol, 2021, 25(2):120-130.
[17] Bamberg K, William-Olsson L, Johansson U, et al. The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone[J]. J Renin Angiotensin Aldosterone Syst, 2019, 20(1):1470320319827449.
[18] Bamberg K, Johansson U, Edman K, et al. Preclinical pharmacology of AZD9977: a novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion[J]. PLoS One, 2018, 13(2):e0193380.
[19] Erlandsson F, Albayaty M, Chialda L, et al. Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator[J]. Br J Clin Pharmacol, 2018, 84(7):1486-1493.
[20] Jaisser F, Tan X, Chi S, et al. The non-steroidal mineralocorticoid receptor antagonist KBP-5074 limits albuminuria and has improved therapeutic index compared with eplerenone in a rat model with mineralocorticoid-induced renal injury[J]. Front Pharmacol 2021, 12:604928.
[21] Bakris G, Pergola PE, Delgado B, et al. Effect of KBP-5074 on blood pressure in advanced chronic kidney disease: results of the BLOCK-CKD study[J]. Hypertension, 2021, 78(1):74-81.
[22] Bakris G, Yang YF, Pitt B. Mineralocorticoid receptor antagonists for hypertension management in advanced chronic kidney disease: BLOCK-CKD trial[J]. Hypertension, 2020, 76(1):144-149.
[23] Luettges KBM, Diemer JN. Finerenone reduces renal RORγt γδ T cells and protects against cardiorenal damage[J]. Am J Nephrol, 2022, 53(7):552-564.
[24] Grune J, Beyhoff N, Smeir E, et al. Selective mineralocorticoid receptor cofactor modulation as molecular basis for finerenone's antifibrotic activity[J]. Hypertension, 2018, 71(4):599-608.
[25] Filippatos G, Anker SD, Agarwal R, et al. Finerenone and cardiovascular outcomes in patients with chronic kidney disease and type 2 diabetes[J]. Circulation, 2021, 143(6):540-552.
[26] Rico-Mesa JS, White A, Ahmadian-Tehrani A, et al. Mineralocorticoid receptor antagonists: a comprehensive review of finerenone[J]. Curr Cardiol Rep, 2020, 22(11):140.
[27] Bakris GL, Agarwal R, Anker SD, et al. Design and baseline characteristics of the finerenone in reducing kidney failure and disease progression in diabetic kidney disease trial[J]. Am J Nephrol, 2019, 50(5):333-344.
[28] Bakris GL, Agarwal R, Anker SD, et al. Effect of finerenone on chronic kidney disease outcomes in type 2 diabetes[J]. N Engl J Med, 2020, 383(23):2219-2229.
[29] Ruilope LM, Agarwal R, Anker SD, et al. Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial[J]. Am J Nephrol, 2019, 50(5):345-356.
[30] Pitt B, Filippatos G, Agarwal R, et al. Cardiovascular events with finerenone in kidney disease and type 2 diabetes[J]. N Engl J Med, 2021, 385(24):2252-2263.