索引超出了数组界限。 文章摘要
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[1]高璐,王祁,赵博,等.TRPV1和TRPA1通道在心血管疾病中的作用[J].国际心血管病杂志,2024,01:4-6,10.
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TRPV1和TRPA1通道在心血管疾病中的作用(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2024年01期
页码:
4-6,10
栏目:
综述
出版日期:
2024-01-22

文章信息/Info

Title:
-
作者:
高璐王祁赵博屈新亮王斌李敏仪卫培峰董泰玮高峰李敏
712046 西安,陕西中医药大学药学院
Author(s):
-
关键词:
瞬时受体电位通道瞬时受体电位香草酸亚型1 瞬时受体电位锚蛋白1 心 血管疾病
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2024.01.002
文献标识码:
-
摘要:
瞬时受体电位(TRP)通道为机体重要的非选择性阳离子通道,瞬时受体电位 香草酸亚型1(TRPV1)属于TRP 通道香草酸受体亚型家族成员,瞬时受体电位锚蛋白1 (TRPA1)属于TRP 通道超家族成员。TRPV1 和TRPA1 通道可调节血管内皮细胞和心肌 细胞功能,其异常表达及功能改变与心血管疾病的发生发展关系密切。TRPV1 通道参与心 肌梗死后心脏保护和血压调节。TRPA1 通道参与调节血流量、血管生成和心肌细胞凋亡。 TRPV1 和TRPA1 通道有望成为心血管疾病的治疗靶点。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81303243);陕西中医药大学创新 团队项目(2019-QN02);陕西省科技厅项目(2022SF-270) 通信作者:李敏,E-mail:413159921@qq.com
更新日期/Last Update: 2024-01-22