[1]朵杰,白洁,韩琼.微小RNA-17-5p通过靶向调控TP53INP1的表达对
急性心肌梗死后心室重构的影响[J].国际心血管病杂志,2022,02:112-116.
DUO Jie,BAI Jie,HAN Qiong..The effect of miR-17-5p on ventricular remodeling after acute myocardial infarction by
targeting the expression of TP53INP1[J].International Journal of Cardiovascular Disease,2022,02:112-116.
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微小RNA-17-5p通过靶向调控TP53INP1的表达对
急性心肌梗死后心室重构的影响(PDF)
《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]
- 期数:
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2022年02期
- 页码:
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112-116
- 栏目:
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综述
- 出版日期:
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2022-06-01
文章信息/Info
- Title:
-
The effect of miR-17-5p on ventricular remodeling after acute myocardial infarction by
targeting the expression of TP53INP1
- 作者:
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朵杰; 白洁; 韩琼
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目的:探讨微小RNA(miRNA)miR-17-5p 通过靶向调控肿瘤蛋白53 诱导性
核蛋白1(TP53INP1)的表达对急性心肌梗死(AMI)后心室重构的影响。方法:选取成年
miR-17-5p-/-、miR-17-5p+/+和正常型SPF 级昆明种小鼠各20 只,采用随机数字表法分为假
手术组、AMI 组、miR-17-5p-/- 假手术组、miR-17-5p-/-AMI 组,miR-17-5p+/+假手术组和
miR-17-5p+/+AMI 组,每组10 只,雌雄各半。构建小鼠AMI 模型,采用超
- Author(s):
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DUO Jie; BAI Jie; HAN Qiong.
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Department of
Hypertension, Qinghai Cardiovascular and Cerebrovascular Disease Hospital, Xining 810000,
China
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- 关键词:
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- Keywords:
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MiR-17-5p; Tumor protein 53-inducible nuclear protein 1; Acute
myocardial infarction; Ventricular remodeling
- 分类号:
-
-
- DOI:
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10.3969/j.issn.1673-6583.2022.02.015
- 文献标识码:
-
-
- 摘要:
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微小RNA-17-5p ;肿瘤蛋白53 诱导性核蛋白1 ;急性心肌梗死;心室重构
- Abstract:
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Objective: To investigate the effect of miR-17-5p on ventricular remodeling
after acute myocardial infarction (AMI) by targeting the expression level of tumor protein
53-inducible nuclear protein 1 (TP53INP1). Methods: Twenty adult Kunming SPF mice with
m
备注/Memo
- 备注/Memo:
-
作者单位:810000 西宁, 青海省心脑血管病专科医院高血压科
通信作者:朵杰, E-mail:commendf@sina.com
更新日期/Last Update:
2022-06-01