[1]李文霞,刘文举,陈漠水,等.经皮冠状动脉介入治疗对急性心肌梗死患者胶原Ⅰ、Ⅲ和Fibulin-5的影响[J].国际心血管病杂志,2018,03:183-185.
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经皮冠状动脉介入治疗对急性心肌梗死患者胶原Ⅰ、Ⅲ和Fibulin-5的影响(PDF)
《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]
- 期数:
- 2018年03期
- 页码:
- 183-185
- 栏目:
- 经验交流
- 出版日期:
- 2018-05-25
文章信息/Info
- Title:
- -
- 作者:
- 李文霞; 刘文举; 陈漠水; 张光星; 梁开坚
- 571700 海南省儋州市人民医院心内科(李文霞,刘文举); 571700 海口市人民医院心内科(陈漠水); 571700 海南医学院附属第一医院心内科(张光星); 571700 海南省白沙县人民医院内科(梁开坚)
- Author(s):
- -
- Keywords:
- -
- 分类号:
- -
- DOI:
- 10.3969/j.issn.1673-6583.2018.03.015
- 文献标识码:
- -
- 摘要:
- 目的:观察经皮冠状动脉介入治疗(PCI)对心肌细胞外基质重构的影响。方法:选择急性ST段抬高型前壁心肌梗死患者47例,按照是否行急诊 PCI 分为急诊PCI组(n=32)和非PCI组(n=15),并设置同期稳定性冠状动脉粥样硬化性心脏病患者30例为对照组。比较3组患者入院即刻,PCI术后1、7、30、45 d血清胶原Ⅰ型C端胶原前肽(PⅠCP)、Ⅲ型N端胶原前肽(PⅢNP)及Fibulin-5水平。结果:不同处理方法对患者心肌细胞外基质重构有显著影响。对照组血清中PⅠCP、PⅢ
- Abstract:
- -
参考文献/References
[1] Deng CM, Huang J, Liu D. Investigation of the mechanism of extracellular matrix remodelling in patients with dilated cardiomyopathy[J]. Modern Medicine Health, 2002, 18(12):1053-1054.
[2] Pauschinger M, Chandrasekharan K, Li J, et al. Mechanisms of extracellular matrix remodeling in dilated cardiomyopathy[J]. Herz, 2002, 27(7):677-682.
[3] Chan W, Duffy SJ, White DA, et al. Acute left ventricular remodeling following myocardial infarction: coupling of regional healing with remote extracellular matrix expansion[J]. JACC Cardiovasc Imaging, 2012, 5(9):884-893.
[4] Dinh W, Füth R, Scheffold T, et al. Increased serum levels of tissue inhibitor of metalloproteinase-1 in patients with acute myocardial infarction[J]. Int Heart J, 2009, 50(4):421-431.
[5] Weir RA, Miller AM, Murphy GE, et al. Serum soluble ST2 A potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction[J]. J Am Coll Cardiol, 2010, 55(3):243-250.
[6] Bruckner BA, Razeghi P, Stetson S, et al. Degree of cardiac fibrosis and hypertrophy at time of implantation predicts myocardial improvement during left ventricular assist device support[J]. J Heart Lung Transplant, 2004, 23(1):36-42.
[7] Jugdutt BI, Idikio H, Uwiera RR. Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction[J]. Mol Cell Biochem, 2007, 303(1/2):27-38.
[8] Hrslev-Petersen K, Kim KY, Pedersen LR, et al. Serum aminoterminal type Ⅲ procollagen peptide. Relation to biosynthesis of collagen type Ⅲ in experimentally induced granulation tissue in rats[J]. APMIS, 1988, 96(9):793-804.
[9] Yanagisawa H, Davis EC, Starcher BC, et al. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo[J]. Nature, 2002, 415(6868):168-171.
[10] Hirai M, Ohbayashi T, Horiguchi M, et al. Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo[J]. J Cell Biol, 2007, 176(7):1061-1071.
[11] 郁秀娟, 丁晓梅.心肌梗死后心室重构研究进展[J]. 中华临床医师杂志(电子版), 2013, 7(2):723-726.
[12] Bershteǐn LL, Novikov VI, Vishnevskiǐ ALU, et al. Prediction of left ventricular remodeling after acute myocardial infarction[J]. Kardiologiia, 2011, 51(3):17-23.
[13] Zornoff LA, Paiva SA, Duarte DR, et al. Ventricular remodeling after myocardial infarction: concepts and clinical implications[J]. Arq Bras Cardiol, 2009, 92(2):150-164.
[14] Radovan J, Vaclav P, Petr W, et al. Changes of collagen metabolism predict the left ventricular remodeling after myocardial infarction[J]. Mol Cell Biochem, 2006, 293(1/2):71-78..
[15] Tayebiee MH, adyenrj MF, Lip GY.Extracellular matrix biology:a new frontier in linking the pathology and therapy of hypertension?[J]. J Hypertens, 2003, 21(12):2211-2218.
[16] Yang F, Yang XP, Liu YH, et al. Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction[J]. Hypertension, 2004, 43(2):229-236.
[17] Peng H, Carretero OA, Raij L, et al. Antifibrotic effects of N-acetyl-seryl-aspartyl-Lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats[J]. Hypertension, 2001, 37(2 Pt 2):794-800.
[18] Kong CH, Lin XY, Woo CC, et al. Characteristics of aortic wall extracellular matrix in patients with acute myocardial infarction: tissue microarray detection of collagen Ⅰ, collagen Ⅲ and elastin levels[J]. Interact Cardiovasc Thorac Surg, 2013, 16(1):11-15.
[19] 彭林林, 吴强, 杨天和, 等.血运重建术对急性心肌梗死患者心脏胶原重塑的影响[J].贵州医药, 2010, 24(1):11-13.
备注/Memo
- 备注/Memo:
-
基金项目:海南省卫生厅普通科研项目(琼卫2013资助-015号)
通信作者:刘文举,Email:li53184493@qq.com
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