|本期目录/Table of Contents|

[1]付国强,曹义战,仲月霞,等.N-3多不饱和脂肪酸的抗炎效应对C57BL/6-PD-1-/-基因敲除小鼠心房电重构的影响[J].国际心血管病杂志,2016,04:235-238.
　FU Guoqiang,CAO Yizhan,ZHONG Yuexia,et al.N-3 polyunsaturated fatty acids prevents atrial electrical remodeling by inhibiting inflammation in C57BL/6-PD-1-/- mice[J].International Journal of Cardiovascular Disease,2016,04:235-238.
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N-3多不饱和脂肪酸的抗炎效应对C57BL/6-PD-1-/-基因敲除小鼠心房电重构的影响(PDF)

《国际心血管病杂志》[ISSN:1006-6977/CN:61-1281/TN]

期数:
2016年04期
页码:
235-238
栏目:
出版日期:
2016-07-20

文章信息/Info

Title:
N-3 polyunsaturated fatty acids prevents atrial electrical remodeling by inhibiting inflammation in C57BL/6-PD-1-/- mice
作者:
付国强; 曹义战; 仲月霞; 田小溪; 王伯良
710038 西安,第四军医大学唐都医院急诊科
Author(s):
FU Guoqiang;  CAO Yizhan; ZHONG Yuexia;  TIAN Xiaoxi; WANG Boliang.
Department of Emergency, Tangdu Hospital, Fourth Military Medical University, ShanXi 710038, China
关键词:
PD-1基因敲除; 炎性细胞因子; 心房电重构; 心房颤动; N-3多不饱和脂肪酸
Keywords:
PD-1 deficiency;  Inflammatory cytokines;  Atrial electricity remodeling;  Atrial fibrillation;  N-3 polyunsaturated fatty acids
分类号:
-
DOI:
10.3969/j.issn.1673-6583.2016.04.013
文献标识码:
-
摘要:
目的:观察N-3多不饱和脂肪酸(PUFAs)饲养对C57BL/6-PD-1-/-小鼠体内炎症和心房电重构的影响。方法:观察和比较C57BL/6、PD-1-/-和PUFAs组小鼠的血清炎性细胞因子表达水平和心房有效不应期。结果:与C57BL/6组小鼠相比,PD-1-/-组小鼠血清白细胞介素(IL)-2、IL-4、IL-6、IL-10、IL-17A、肿瘤坏死因子(TNF)和γ干扰素(IFN-γ)水平明显升高,同时PD-1-/-
Abstract:
Objective:To investigate the effect of dietary N-3 polyunsaturated fatty acids on the inflammation and atrial electrical remodeling in C57BL/6-PD-1-/- mice.Methods:The expression of inflammatory cytokines and the atrial effective refractory per

参考文献/References

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81070161) 作者单位:710038 西安,第四军医大学唐都医院急诊科 通信作者:王伯良,Email:wliang@fmmu.edu.cn
更新日期/Last Update: 2016-07-20